Artistic rendering of a heart
© Pixabay

Hübner Lab

Genetics and Genomics of Cardiovascular Diseases

Team

Group Leader

Prof. Dr. Norbert Hübner
Prof. Dr. Norbert Hübner
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.09
9406-2530

Scientist

Dr. Henrike Maatz
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.06
9406-3037
Dr. Franz Rüschendorf
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.10
9406-3378
Dr. Kathrin Saar
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: R 0.06
3534
Dr. Catherine Sargent
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.17
Dr. Sebastiaan van Heesch
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.17

Secretariat

Maren Beckmann
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.07
+49-30-9406-3512

Technical Assistants

Susanne Blachut
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.50
9406-3269
Gabriele Born
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.50
94063458
Mathias Gerhard
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.13
Oliver Hummel
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.10
Dr. Giannino Patone
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.10
9406-3441
Sabine Schmidt
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.22

PhD student

Maria Bikou
87: Timoféeff-Ressovsky-House (Genomcentrum)
2531
Eric Lars-Helge Lindberg
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.13
2531
Monika Litvinukova
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.13
Clara-Louisa Maria Müller
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.17
9406-2930
Valentin Schneider-Lunitz
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 0.13
2531
Jana Felicitas Schulz
87: Timoféeff-Ressovsky-House (Genomcentrum)
Room: 017
3430

Research

Medical Genomics and Genetics of Cardiovascular and Metabolic Diseases

Publications

in Diabetes

An integrated understanding of the molecular mechanisms how adipose tissue metabolism affects long-term body weight maintenance

K. Mai et al.
in J Bone Miner Res

An N-ethyl-N-nitrosourea (ENU)-induced Tyr265Stop mutation of the DNA polymerase accessory subunit gamma 2 (Polg2) is associated with renal calcification in mice

C.M. Gorvin et al.
in Pflugers Arch

Telmisartan prevents diet-induced obesity and preserves leptin transport across the blood-brain barrier in high-fat diet-fed mice

F. Schuster et al.
in J Allergy Clin Immunol

Evaluation of food allergy candidate loci in the Genetics of Food Allergy Study

I. Marenholz et al.
in Sci Rep

Thyroid cancer cells in space during the TEXUS-53 sounding rocket mission - The THYROID Project

S. Kopp et al.
in Cell Physiol Biochem

Pathway analysis hints towards beneficial effects of long-term vibration on human chondrocytes

R. Lützenberg et al.
in Diabetes

Nrf2-mediated antioxidant defense and peroxiredoxin 6 are linked to biosynthesis of palmitic acid ester of 9-hydroxystearic acid

O. Kuda et al.
in J Invest Dermatol

SMARCAD1 haploinsufficiency underlies Huriez syndrome and associated skin cancer susceptibility

C. Günther et al.
in J Allergy Clin Immunol

Eleven loci with new reproducible genetic associations with allergic disease risk

M.A. Ferreira et al.
in J Allergy Clin Immunol

A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma

Y. Asai et al.

News

Stock Photo newspapers
Press Release No. 9 Berlin

Two MDC scientists receive ERC grants worth several million euros

Basic researchers Gary Lewin and Norbert Hübner are investigating the anchoring of ion channels and micropeptides in heart muscle cells.
Artistic rendering of a heart
Science

By stimulating the excessive buildup of connective tissue, signaling molecule contributes to heart disease

Acute ischemia (lack of blood flow) and sustained high blood pressure have grave consequences for...
Science

By stimulating the excessive buildup of connective tissue, signaling molecule contributes to heart disease

One of the causes of heart failure is the formation of excess connective tissue. An international team of researchers has discovered a specific treatment approach involving the signaling molecule interleukin 11. Their findings have now been published in the journal Nature.
Cardiomyocytes
Press Release No. 23 Berlin

MDC receives funding to collaborate on Human Cell Atlas

Organs and tissues are comprised of very different types of cells. The heart, for example, contains...
DCM Hearts
Press Release No. 21 Berlin

Study of transplanted hearts reveals risk gene for cardiovascular disease

In the largest transcriptome study to date, an international research team analysed the RNA of transplanted hearts and discovered a number of new risk factors for dilated cardiomyopathy and other heart conditions which could thus be recognised more easily in future.
Stock Photo newspapers
Science

Two Humboldt award winners are coming to the MDC as visiting scientists

David H. Gutmann, the US neurologist, and Prof. Maike Sander, a diabetes researcher at the University of California, San Diego, USA, have now been granted the Humboldt Research Award by the Alexander von Humboldt Foundation.
Science

Only apparently healthy: How titin gene mutations affect heart function

The MDC research group led by Norbert Hübner has discovered that mutations in the titin gene have previously unknown effects on the heart function of healthy individuals. These mutations are present in one percent of the general population.
Science By Russell Hodge

Finding the regulators

Eleonora Adami of the Hübner lab links the regulation of protein synthesis to disease in the best...
Science

New level of gene regulation plays a role in cardiovascular diseases

When genes are read at the wrong time or in the wrong place they can cause a disease. Less well...
RBM20
Science By Russell Hodge

A broken tool and broken hearts

The analysis of the human genome showed that our DNA contains fewer genes than most scientists...
Prof. Dr. Norbert Hübner
Prof. Dr. Norbert Hübner
Contact
Phone: 9406-2530
Max-Delbrück-Centrum für Molekulare Medizin (MDC)
Robert-Rössle-Str. 10
13125 Berlin, Deutschland
Building 87, Room 0.09

Research Topics