© Pixabay Hübner Lab Genetics and Genomics of Cardiovascular Diseases Profile Team Research Publications News Profile Team Research Publications News Profile Team Group Leader Prof. Dr. Norbert Hübner 87: Timoféeff-Ressovsky-Haus Room: 0.09 nhuebner@mdc-berlin.de +49 30 9406-2530 Scientist Dr. Ning Liang 87: Timoféeff-Ressovsky-Haus Room: 0.10 Ning.Liang@mdc-berlin.de +49 30 9406-4384 Dr. Henrike Maatz 87: Timoféeff-Ressovsky-Haus Room: 0.06 h.maatz@mdc-berlin.de +49 30 9406-3037 Dr. Jorge Ruiz Orera 87: Timoféeff-Ressovsky-Haus Room: 0.17 Jorge.RuizOrera@mdc-berlin.de +49 30 9406-2930 Dr. Kathrin Saar 87: Timoféeff-Ressovsky-Haus Room: 0.06 ksaar@mdc-berlin.de +49 30 9406-3534 Secretariat Nathalie Böhm 87: Timoféeff-Ressovsky-Haus Room: 0.07 Nathalie.Boehm@mdc-berlin.de +49 30 9406-3512 Technical Assistants Susanne Blachut 87: Timoféeff-Ressovsky-Haus Room: 0.50 s.blachut@mdc-berlin.de +49 30 9406-3269 Mathias Gerhard 87: Timoféeff-Ressovsky-Haus Room: 0.13 Oliver Hummel 87: Timoféeff-Ressovsky-Haus Room: 0.10 o.hummel@mdc-berlin.de Dr. Giannino Patone 87: Timoféeff-Ressovsky-Haus Room: 0.10 giannino.patone@mdc-berlin.de +49 30 9406-3441 Sabine Schmidt 87: Timoféeff-Ressovsky-Haus Room: 0.22 PhD student Nikita Shyam Dewani 87: Timoféeff-Ressovsky-Haus Room: 0.13 Nikita.Dewani@mdc-berlin.de +49 30 9406-2531 Johannes Greiner 87: Timoféeff-Ressovsky-Haus Room: 0.13 Eric Lars-Helge Lindberg 87: Timoféeff-Ressovsky-Haus Room: 0.13 +49 30 9406-2531 Monika Litvinukova 87: Timoféeff-Ressovsky-Haus Room: 0.13 Monika.Litvinukova@mdc-berlin.de Clara-Louisa Sandmann 87: Timoféeff-Ressovsky-Haus Room: 0.17 Clara.Sandmann@mdc-berlin.de +49 30 9406-2930 Valentin Schneider-Lunitz 87: Timoféeff-Ressovsky-Haus Room: 0.13 Valentin.Schneider@mdc-berlin.de +49 30 9406-2531 Jana Felicitas Schulz 87: Timoféeff-Ressovsky-Haus Room: 0.17 JanaFelicitas.Schulz@mdc-berlin.de +49 30 9406-3430 Other Dr. Franz Rüschendorf 87: Timoféeff-Ressovsky-Haus Room: 0.10 +49 30 9406-3378 Doctor Michael Benedikt Mücke 87: Timoféeff-Ressovsky-Haus Room: 0.13 Research Medical Genomics and Genetics of Cardiovascular and Metabolic Diseases Publications March 01, 2021 in Nat Rev Cardiol Myocarditis and inflammatory cardiomyopathy: current evidence and future directions C. Tschöpe E. Ammirati B. Bozkurt A.L.P. Caforio L.T. Cooper S.B. Felix J.M. Hare B. Heidecker S. Heymans N. Hübner S. Kelle K. Klingel H. Maatz A.S. Parwani F. Spillmann R.C. Starling H. Tsutsui P. Seferovic S. Van Linthout February 11, 2021 in Stem Cell Rep Apple peel and flesh contain pro-neurogenic compounds M. Ichwan T.L. Walker Z. Nicola J. Ludwig-Müller C. Böttcher R.W. Overall V.S. Adusumilli M. Bulut A.M. Sykes N. Hübner G. Ramirez-Rodriguez L. Ortiz-López E.A. Lugo-Hernández G. Kempermann February 01, 2021 in J Cereb Blood Flow Metab Cerebral angiogenesis ameliorates pathological disorders in Nemo-deficient mice with small-vessel disease Y. Jiang K. Müller M.A. Khan J.C. Assmann J. Lampe K. Kilau M. Richter M. Kleint D.A. Ridder N. Hübner M. Schmidt-Supprian J. Wenzel M. Schwaninger January 27, 2021 in Nat Commun Endophilin A2 deficiency protects rodents from autoimmune arthritis by modulating T cell activation U. Norin C. Rintisch L. Meng F. Forster D. Ekman J. Tuncel K. Klocke J. Bäcklund M. Yang M.Y Bonner G.F. Lahore J. James K. Shchetynsky M. Bergquist I. Gjertsson N. Hubner L. Bäckdahl R. Holmdahl January 27, 2021 in Nat Commun Uncovering de novo gene birth in yeast using deep transcriptomics W.R. Blevins J. Ruiz-Orera X. Messeguer B. Blasco-Moreno J.L. Villanueva-Cañas L. Espinar J. Díez L.B. Carey M.M. Albà January 26, 2021 in Hum Genet A biallelic variant in CLRN2 causes non-syndromic hearing loss in humans B. Vona N. Mazaheri S.J. Lin L.A. Dunbar R. Maroofian H. Azaiez K.T. Booth S. Vitry A. Rad F. Rüschendorf P. Varshney B. Fowler C. Beetz K.N. Alagramam D. Murphy G. Shariati A. Sedaghat H. Houlden C. Petree S. VijayKumar R.J.H. Smith T. Haaf A. El-Amraoui M.R. Bowl G.K. Varshney H. Galehdari January 01, 2021 in Prog Biophys Mol Biol Transcriptional signatures regulated by TRPC1/C4-mediated Background Ca(2+) entry after pressure-overload induced cardiac remodelling J.E. Camacho Londoño V. Kuryshev M. Zorn K. Saar Q. Tian N. Hübner P. Nawroth A. Dietrich L. Birnbaumer P. Lipp C. Dieterich M. Freichel December 17, 2020 in Nature Cells of the adult human heart M. Litviňuková C. Talavera-López H. Maatz D. Reichart C.L. Worth E.L. Lindberg M. Kanda K. Polanski M. Heinig M.l Lee E.R. Nadelmann K. Roberts L. Tuck E.S. Fasouli D.M. DeLaughter B. McDonough H. Wakimoto J.M. Gorham S. Samari K.T. Mahbubani K. Saeb-Parsy G. Patone J.J. Boyle H. Zhang H. Zhang A. Viveiros G.Y. Oudit O. Bayraktar J.G. Seidman C.E. Seidman M. Noseda N. Hubner S.A. Teichmann November 19, 2020 in Nature LifeTime and improving European healthcare through cell-based interceptive medicine N. Rajewsky G. Almouzni S.A. Gorski S. Aerts I. Amit M.G. Bertero C. Bock A.L. Bredenoord G. Cavalli S. Chiocca H. Clevers B. De Strooper A. Eggert J. Ellenberg X.M. Fernández M. Figlerowicz S.M. Gasser N. Hubner J. Kjems J.A. Knoblich G. Krabbe P. Lichter S. Linnarsson J.C. Marine J. Marioni M.A. Marti-Renom M.G. Netea D. Nickel M. Nollmann H.R. Novak H. Parkinson S. Piccolo I. Pinheiro A. Pombo C. Popp W. Reik S. Roman-Roman P. Rosenstiel J.L. Schultze O. Stegle A. Tanay G. Testa D. Thanos F.J. Theis M.E. Torres-Padilla A. Valencia C. Vallot A. van Oudenaarden M. Vidal T. Voet November 11, 2020 in Genes Genetic spectrum of syndromic and non-syndromic hearing loss in Pakistani families J. Doll B. Vona L. Schnapp F. Rüschendorf I. Khan S. Khan N. Muhammad S. Alam Khan H. Nawaz A. Khan N. Ahmad S.M. Kolb L. Kühlewein J.D.J. Labonne L.C. Layman M.A.H. Hofrichter T. Röder M. Dittrich T. Müller T.D. Graves I.K. Kong I. Nanda H.G. Kim T. Haaf Pagination Current page 1 Page 2 Page 3 Page 4 … Next page ›› Last page Last » News Press Release No. 48 October 29, 2020 Berlin Not all hearts are the same An international research team recently created the first atlas of the human heart. Now the scientists want to add a new dimension to the project: diversity. They are being supported by an additional Seed Networks grant from the Chan Zuckerberg Initiative. Press Release No. 42 September 24, 2020 Berlin An in-depth atlas of the heart Researchers from three continents have produced a first extensive draft of a cell atlas of the human heart to understand how this vital organ functions and to shed light on what goes wrong in cardiovascular disease. As the team reports in Nature, it reveals a huge cellular and molecular diversity. Press Release No. 18 April 23, 2020 Berlin Likely Entrypoints for SARS-CoV-2 Two specific cell types in the nose have been identified as likely initial infection points for the novel coronavirus that causes COVID-19. Using data from the Human Cell Atlas, scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that SARS-CoV-2 uses to get into our cells. Press Release No. 30 June 21, 2019 Berlin Straight to the heart An international team of researchers are seeking to explore the heart at a depth that was previously impossible. They have now received a grant of nearly four million US dollars from the Chan Zuckerberg Initiative – as one of the 38 Seed Networks working on the Human Cell Atlas. MDC researcher Norbert Hübner is co-coordinator of the project. Press Release No. 25 May 30, 2019 Berlin Unknown mini-proteins in the heart A team led by Professor Norbert Hübner’s MDC research group has observed the human heart cells’ “protein factories” in action, examining the entire tissue for the very first time. In an article published in Cell, the group reveals their surprising discoveries and the possibilities they contain for the future treatment of heart disease. Press Release No. 17 April 26, 2019 Berlin Unlocking the secrets of heart cells A heart seems to be pure physics: valves open and close, blood flows, electrical impulses control the heartbeat. A German-British research team is now looking at it in a different way. It will break down the heart into its smallest components - the cells - and unlock their secrets. The project is now being funded with 2.5 million euros for three years. Press Release No. 9 April 13, 2018 Berlin Two MDC scientists receive ERC grants worth several million euros Basic researchers Gary Lewin and Norbert Hübner are investigating the anchoring of ion channels and micropeptides in heart muscle cells. Science November 13, 2017 By stimulating the excessive buildup of connective tissue, signaling molecule contributes to heart disease Acute ischemia (lack of blood flow) and sustained high blood pressure have grave consequences for... Science November 13, 2017 By stimulating the excessive buildup of connective tissue, signaling molecule contributes to heart disease One of the causes of heart failure is the formation of excess connective tissue. An international team of researchers has discovered a specific treatment approach involving the signaling molecule interleukin 11. Their findings have now been published in the journal Nature. Press Release No. 23 October 16, 2017 Berlin MDC receives funding to collaborate on Human Cell Atlas Organs and tissues are comprised of very different types of cells. The heart, for example, contains... Pagination Current page 1 Page 2 Page 3 Page 4 Next page ›› Last page Last » Prof. Dr. Norbert Hübner Contact nhuebner@mdc-berlin.de Phone: +49 30 9406-2530 Max-Delbrück-Centrum für Molekulare Medizin (MDC) Robert-Rössle-Straße 10 13125 Berlin, Deutschland Building 87, Room 0.09 Research Topics Genetics & Genomics Gene Expression Regulation & RNA Biology Cardiovascular Research
Team Group Leader Prof. Dr. Norbert Hübner 87: Timoféeff-Ressovsky-Haus Room: 0.09 nhuebner@mdc-berlin.de +49 30 9406-2530 Scientist Dr. Ning Liang 87: Timoféeff-Ressovsky-Haus Room: 0.10 Ning.Liang@mdc-berlin.de +49 30 9406-4384 Dr. Henrike Maatz 87: Timoféeff-Ressovsky-Haus Room: 0.06 h.maatz@mdc-berlin.de +49 30 9406-3037 Dr. Jorge Ruiz Orera 87: Timoféeff-Ressovsky-Haus Room: 0.17 Jorge.RuizOrera@mdc-berlin.de +49 30 9406-2930 Dr. Kathrin Saar 87: Timoféeff-Ressovsky-Haus Room: 0.06 ksaar@mdc-berlin.de +49 30 9406-3534 Secretariat Nathalie Böhm 87: Timoféeff-Ressovsky-Haus Room: 0.07 Nathalie.Boehm@mdc-berlin.de +49 30 9406-3512 Technical Assistants Susanne Blachut 87: Timoféeff-Ressovsky-Haus Room: 0.50 s.blachut@mdc-berlin.de +49 30 9406-3269 Mathias Gerhard 87: Timoféeff-Ressovsky-Haus Room: 0.13 Oliver Hummel 87: Timoféeff-Ressovsky-Haus Room: 0.10 o.hummel@mdc-berlin.de Dr. Giannino Patone 87: Timoféeff-Ressovsky-Haus Room: 0.10 giannino.patone@mdc-berlin.de +49 30 9406-3441 Sabine Schmidt 87: Timoféeff-Ressovsky-Haus Room: 0.22 PhD student Nikita Shyam Dewani 87: Timoféeff-Ressovsky-Haus Room: 0.13 Nikita.Dewani@mdc-berlin.de +49 30 9406-2531 Johannes Greiner 87: Timoféeff-Ressovsky-Haus Room: 0.13 Eric Lars-Helge Lindberg 87: Timoféeff-Ressovsky-Haus Room: 0.13 +49 30 9406-2531 Monika Litvinukova 87: Timoféeff-Ressovsky-Haus Room: 0.13 Monika.Litvinukova@mdc-berlin.de Clara-Louisa Sandmann 87: Timoféeff-Ressovsky-Haus Room: 0.17 Clara.Sandmann@mdc-berlin.de +49 30 9406-2930 Valentin Schneider-Lunitz 87: Timoféeff-Ressovsky-Haus Room: 0.13 Valentin.Schneider@mdc-berlin.de +49 30 9406-2531 Jana Felicitas Schulz 87: Timoféeff-Ressovsky-Haus Room: 0.17 JanaFelicitas.Schulz@mdc-berlin.de +49 30 9406-3430 Other Dr. Franz Rüschendorf 87: Timoféeff-Ressovsky-Haus Room: 0.10 +49 30 9406-3378 Doctor Michael Benedikt Mücke 87: Timoféeff-Ressovsky-Haus Room: 0.13
Publications March 01, 2021 in Nat Rev Cardiol Myocarditis and inflammatory cardiomyopathy: current evidence and future directions C. Tschöpe E. Ammirati B. Bozkurt A.L.P. Caforio L.T. Cooper S.B. Felix J.M. Hare B. Heidecker S. Heymans N. Hübner S. Kelle K. Klingel H. Maatz A.S. Parwani F. Spillmann R.C. Starling H. Tsutsui P. Seferovic S. Van Linthout February 11, 2021 in Stem Cell Rep Apple peel and flesh contain pro-neurogenic compounds M. Ichwan T.L. Walker Z. Nicola J. Ludwig-Müller C. Böttcher R.W. Overall V.S. Adusumilli M. Bulut A.M. Sykes N. Hübner G. Ramirez-Rodriguez L. Ortiz-López E.A. Lugo-Hernández G. Kempermann February 01, 2021 in J Cereb Blood Flow Metab Cerebral angiogenesis ameliorates pathological disorders in Nemo-deficient mice with small-vessel disease Y. Jiang K. Müller M.A. Khan J.C. Assmann J. Lampe K. Kilau M. Richter M. Kleint D.A. Ridder N. Hübner M. Schmidt-Supprian J. Wenzel M. Schwaninger January 27, 2021 in Nat Commun Endophilin A2 deficiency protects rodents from autoimmune arthritis by modulating T cell activation U. Norin C. Rintisch L. Meng F. Forster D. Ekman J. Tuncel K. Klocke J. Bäcklund M. Yang M.Y Bonner G.F. Lahore J. James K. Shchetynsky M. Bergquist I. Gjertsson N. Hubner L. Bäckdahl R. Holmdahl January 27, 2021 in Nat Commun Uncovering de novo gene birth in yeast using deep transcriptomics W.R. Blevins J. Ruiz-Orera X. Messeguer B. Blasco-Moreno J.L. Villanueva-Cañas L. Espinar J. Díez L.B. Carey M.M. Albà January 26, 2021 in Hum Genet A biallelic variant in CLRN2 causes non-syndromic hearing loss in humans B. Vona N. Mazaheri S.J. Lin L.A. Dunbar R. Maroofian H. Azaiez K.T. Booth S. Vitry A. Rad F. Rüschendorf P. Varshney B. Fowler C. Beetz K.N. Alagramam D. Murphy G. Shariati A. Sedaghat H. Houlden C. Petree S. VijayKumar R.J.H. Smith T. Haaf A. El-Amraoui M.R. Bowl G.K. Varshney H. Galehdari January 01, 2021 in Prog Biophys Mol Biol Transcriptional signatures regulated by TRPC1/C4-mediated Background Ca(2+) entry after pressure-overload induced cardiac remodelling J.E. Camacho Londoño V. Kuryshev M. Zorn K. Saar Q. Tian N. Hübner P. Nawroth A. Dietrich L. Birnbaumer P. Lipp C. Dieterich M. Freichel December 17, 2020 in Nature Cells of the adult human heart M. Litviňuková C. Talavera-López H. Maatz D. Reichart C.L. Worth E.L. Lindberg M. Kanda K. Polanski M. Heinig M.l Lee E.R. Nadelmann K. Roberts L. Tuck E.S. Fasouli D.M. DeLaughter B. McDonough H. Wakimoto J.M. Gorham S. Samari K.T. Mahbubani K. Saeb-Parsy G. Patone J.J. Boyle H. Zhang H. Zhang A. Viveiros G.Y. Oudit O. Bayraktar J.G. Seidman C.E. Seidman M. Noseda N. Hubner S.A. Teichmann November 19, 2020 in Nature LifeTime and improving European healthcare through cell-based interceptive medicine N. Rajewsky G. Almouzni S.A. Gorski S. Aerts I. Amit M.G. Bertero C. Bock A.L. Bredenoord G. Cavalli S. Chiocca H. Clevers B. De Strooper A. Eggert J. Ellenberg X.M. Fernández M. Figlerowicz S.M. Gasser N. Hubner J. Kjems J.A. Knoblich G. Krabbe P. Lichter S. Linnarsson J.C. Marine J. Marioni M.A. Marti-Renom M.G. Netea D. Nickel M. Nollmann H.R. Novak H. Parkinson S. Piccolo I. Pinheiro A. Pombo C. Popp W. Reik S. Roman-Roman P. Rosenstiel J.L. Schultze O. Stegle A. Tanay G. Testa D. Thanos F.J. Theis M.E. Torres-Padilla A. Valencia C. Vallot A. van Oudenaarden M. Vidal T. Voet November 11, 2020 in Genes Genetic spectrum of syndromic and non-syndromic hearing loss in Pakistani families J. Doll B. Vona L. Schnapp F. Rüschendorf I. Khan S. Khan N. Muhammad S. Alam Khan H. Nawaz A. Khan N. Ahmad S.M. Kolb L. Kühlewein J.D.J. Labonne L.C. Layman M.A.H. Hofrichter T. Röder M. Dittrich T. Müller T.D. Graves I.K. Kong I. Nanda H.G. Kim T. Haaf Pagination Current page 1 Page 2 Page 3 Page 4 … Next page ›› Last page Last »
March 01, 2021 in Nat Rev Cardiol Myocarditis and inflammatory cardiomyopathy: current evidence and future directions C. Tschöpe E. Ammirati B. Bozkurt A.L.P. Caforio L.T. Cooper S.B. Felix J.M. Hare B. Heidecker S. Heymans N. Hübner S. Kelle K. Klingel H. Maatz A.S. Parwani F. Spillmann R.C. Starling H. Tsutsui P. Seferovic S. Van Linthout
February 11, 2021 in Stem Cell Rep Apple peel and flesh contain pro-neurogenic compounds M. Ichwan T.L. Walker Z. Nicola J. Ludwig-Müller C. Böttcher R.W. Overall V.S. Adusumilli M. Bulut A.M. Sykes N. Hübner G. Ramirez-Rodriguez L. Ortiz-López E.A. Lugo-Hernández G. Kempermann
February 01, 2021 in J Cereb Blood Flow Metab Cerebral angiogenesis ameliorates pathological disorders in Nemo-deficient mice with small-vessel disease Y. Jiang K. Müller M.A. Khan J.C. Assmann J. Lampe K. Kilau M. Richter M. Kleint D.A. Ridder N. Hübner M. Schmidt-Supprian J. Wenzel M. Schwaninger
January 27, 2021 in Nat Commun Endophilin A2 deficiency protects rodents from autoimmune arthritis by modulating T cell activation U. Norin C. Rintisch L. Meng F. Forster D. Ekman J. Tuncel K. Klocke J. Bäcklund M. Yang M.Y Bonner G.F. Lahore J. James K. Shchetynsky M. Bergquist I. Gjertsson N. Hubner L. Bäckdahl R. Holmdahl
January 27, 2021 in Nat Commun Uncovering de novo gene birth in yeast using deep transcriptomics W.R. Blevins J. Ruiz-Orera X. Messeguer B. Blasco-Moreno J.L. Villanueva-Cañas L. Espinar J. Díez L.B. Carey M.M. Albà
January 26, 2021 in Hum Genet A biallelic variant in CLRN2 causes non-syndromic hearing loss in humans B. Vona N. Mazaheri S.J. Lin L.A. Dunbar R. Maroofian H. Azaiez K.T. Booth S. Vitry A. Rad F. Rüschendorf P. Varshney B. Fowler C. Beetz K.N. Alagramam D. Murphy G. Shariati A. Sedaghat H. Houlden C. Petree S. VijayKumar R.J.H. Smith T. Haaf A. El-Amraoui M.R. Bowl G.K. Varshney H. Galehdari
January 01, 2021 in Prog Biophys Mol Biol Transcriptional signatures regulated by TRPC1/C4-mediated Background Ca(2+) entry after pressure-overload induced cardiac remodelling J.E. Camacho Londoño V. Kuryshev M. Zorn K. Saar Q. Tian N. Hübner P. Nawroth A. Dietrich L. Birnbaumer P. Lipp C. Dieterich M. Freichel
December 17, 2020 in Nature Cells of the adult human heart M. Litviňuková C. Talavera-López H. Maatz D. Reichart C.L. Worth E.L. Lindberg M. Kanda K. Polanski M. Heinig M.l Lee E.R. Nadelmann K. Roberts L. Tuck E.S. Fasouli D.M. DeLaughter B. McDonough H. Wakimoto J.M. Gorham S. Samari K.T. Mahbubani K. Saeb-Parsy G. Patone J.J. Boyle H. Zhang H. Zhang A. Viveiros G.Y. Oudit O. Bayraktar J.G. Seidman C.E. Seidman M. Noseda N. Hubner S.A. Teichmann
November 19, 2020 in Nature LifeTime and improving European healthcare through cell-based interceptive medicine N. Rajewsky G. Almouzni S.A. Gorski S. Aerts I. Amit M.G. Bertero C. Bock A.L. Bredenoord G. Cavalli S. Chiocca H. Clevers B. De Strooper A. Eggert J. Ellenberg X.M. Fernández M. Figlerowicz S.M. Gasser N. Hubner J. Kjems J.A. Knoblich G. Krabbe P. Lichter S. Linnarsson J.C. Marine J. Marioni M.A. Marti-Renom M.G. Netea D. Nickel M. Nollmann H.R. Novak H. Parkinson S. Piccolo I. Pinheiro A. Pombo C. Popp W. Reik S. Roman-Roman P. Rosenstiel J.L. Schultze O. Stegle A. Tanay G. Testa D. Thanos F.J. Theis M.E. Torres-Padilla A. Valencia C. Vallot A. van Oudenaarden M. Vidal T. Voet
November 11, 2020 in Genes Genetic spectrum of syndromic and non-syndromic hearing loss in Pakistani families J. Doll B. Vona L. Schnapp F. Rüschendorf I. Khan S. Khan N. Muhammad S. Alam Khan H. Nawaz A. Khan N. Ahmad S.M. Kolb L. Kühlewein J.D.J. Labonne L.C. Layman M.A.H. Hofrichter T. Röder M. Dittrich T. Müller T.D. Graves I.K. Kong I. Nanda H.G. Kim T. Haaf
News Press Release No. 48 October 29, 2020 Berlin Not all hearts are the same An international research team recently created the first atlas of the human heart. Now the scientists want to add a new dimension to the project: diversity. They are being supported by an additional Seed Networks grant from the Chan Zuckerberg Initiative. Press Release No. 42 September 24, 2020 Berlin An in-depth atlas of the heart Researchers from three continents have produced a first extensive draft of a cell atlas of the human heart to understand how this vital organ functions and to shed light on what goes wrong in cardiovascular disease. As the team reports in Nature, it reveals a huge cellular and molecular diversity. Press Release No. 18 April 23, 2020 Berlin Likely Entrypoints for SARS-CoV-2 Two specific cell types in the nose have been identified as likely initial infection points for the novel coronavirus that causes COVID-19. Using data from the Human Cell Atlas, scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that SARS-CoV-2 uses to get into our cells. Press Release No. 30 June 21, 2019 Berlin Straight to the heart An international team of researchers are seeking to explore the heart at a depth that was previously impossible. They have now received a grant of nearly four million US dollars from the Chan Zuckerberg Initiative – as one of the 38 Seed Networks working on the Human Cell Atlas. MDC researcher Norbert Hübner is co-coordinator of the project. Press Release No. 25 May 30, 2019 Berlin Unknown mini-proteins in the heart A team led by Professor Norbert Hübner’s MDC research group has observed the human heart cells’ “protein factories” in action, examining the entire tissue for the very first time. In an article published in Cell, the group reveals their surprising discoveries and the possibilities they contain for the future treatment of heart disease. Press Release No. 17 April 26, 2019 Berlin Unlocking the secrets of heart cells A heart seems to be pure physics: valves open and close, blood flows, electrical impulses control the heartbeat. A German-British research team is now looking at it in a different way. It will break down the heart into its smallest components - the cells - and unlock their secrets. The project is now being funded with 2.5 million euros for three years. Press Release No. 9 April 13, 2018 Berlin Two MDC scientists receive ERC grants worth several million euros Basic researchers Gary Lewin and Norbert Hübner are investigating the anchoring of ion channels and micropeptides in heart muscle cells. Science November 13, 2017 By stimulating the excessive buildup of connective tissue, signaling molecule contributes to heart disease Acute ischemia (lack of blood flow) and sustained high blood pressure have grave consequences for... Science November 13, 2017 By stimulating the excessive buildup of connective tissue, signaling molecule contributes to heart disease One of the causes of heart failure is the formation of excess connective tissue. An international team of researchers has discovered a specific treatment approach involving the signaling molecule interleukin 11. Their findings have now been published in the journal Nature. Press Release No. 23 October 16, 2017 Berlin MDC receives funding to collaborate on Human Cell Atlas Organs and tissues are comprised of very different types of cells. The heart, for example, contains... Pagination Current page 1 Page 2 Page 3 Page 4 Next page ›› Last page Last »
Press Release No. 48 October 29, 2020 Berlin Not all hearts are the same An international research team recently created the first atlas of the human heart. Now the scientists want to add a new dimension to the project: diversity. They are being supported by an additional Seed Networks grant from the Chan Zuckerberg Initiative.
Press Release No. 42 September 24, 2020 Berlin An in-depth atlas of the heart Researchers from three continents have produced a first extensive draft of a cell atlas of the human heart to understand how this vital organ functions and to shed light on what goes wrong in cardiovascular disease. As the team reports in Nature, it reveals a huge cellular and molecular diversity.
Press Release No. 18 April 23, 2020 Berlin Likely Entrypoints for SARS-CoV-2 Two specific cell types in the nose have been identified as likely initial infection points for the novel coronavirus that causes COVID-19. Using data from the Human Cell Atlas, scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that SARS-CoV-2 uses to get into our cells.
Press Release No. 30 June 21, 2019 Berlin Straight to the heart An international team of researchers are seeking to explore the heart at a depth that was previously impossible. They have now received a grant of nearly four million US dollars from the Chan Zuckerberg Initiative – as one of the 38 Seed Networks working on the Human Cell Atlas. MDC researcher Norbert Hübner is co-coordinator of the project.
Press Release No. 25 May 30, 2019 Berlin Unknown mini-proteins in the heart A team led by Professor Norbert Hübner’s MDC research group has observed the human heart cells’ “protein factories” in action, examining the entire tissue for the very first time. In an article published in Cell, the group reveals their surprising discoveries and the possibilities they contain for the future treatment of heart disease.
Press Release No. 17 April 26, 2019 Berlin Unlocking the secrets of heart cells A heart seems to be pure physics: valves open and close, blood flows, electrical impulses control the heartbeat. A German-British research team is now looking at it in a different way. It will break down the heart into its smallest components - the cells - and unlock their secrets. The project is now being funded with 2.5 million euros for three years.
Press Release No. 9 April 13, 2018 Berlin Two MDC scientists receive ERC grants worth several million euros Basic researchers Gary Lewin and Norbert Hübner are investigating the anchoring of ion channels and micropeptides in heart muscle cells.
Science November 13, 2017 By stimulating the excessive buildup of connective tissue, signaling molecule contributes to heart disease Acute ischemia (lack of blood flow) and sustained high blood pressure have grave consequences for...
Science November 13, 2017 By stimulating the excessive buildup of connective tissue, signaling molecule contributes to heart disease One of the causes of heart failure is the formation of excess connective tissue. An international team of researchers has discovered a specific treatment approach involving the signaling molecule interleukin 11. Their findings have now been published in the journal Nature.
Press Release No. 23 October 16, 2017 Berlin MDC receives funding to collaborate on Human Cell Atlas Organs and tissues are comprised of very different types of cells. The heart, for example, contains...
Prof. Dr. Norbert Hübner Contact nhuebner@mdc-berlin.de Phone: +49 30 9406-2530 Max-Delbrück-Centrum für Molekulare Medizin (MDC) Robert-Rössle-Straße 10 13125 Berlin, Deutschland Building 87, Room 0.09