The aim of the Einstein Center 3R is to develop animal-free approaches to creating new treatments for human diseases. These approaches should also improve the transferability of laboratory research to patients. The center brings together expertise from Charité – Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin as well as Technische Universität Berlin and was created in 2021 in close cooperation with the Berlin Institute of Health at Charité, the Max Delbrück Center, the German Federal Institute for Risk Assessment, and the Robert Koch Institute.
In line with William Russell and Rex Burch’s 3R principle, the center uses research, education, and communication to consider ways to substitute animal experiments with alternatives (replace), minimize the number of animals used in experiments (reduce), and ease the amount of stress put on animals (refine). Following a successful interim assessment, the center has been granted funding for a further two and a half years until 2026.