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Actin rings of power

Authors

  • Cornelia Schwayer
  • Mateusz Sikora
  • Jana Slováková
  • Roland Kardos
  • Carl-Philipp Heisenberg

Journal

  • Developmental Cell

Citation

  • Dev Cell 37 (6): 493-506

Abstract

  • Circular or ring-like actin structures play important roles in various developmental and physiological processes. Commonly, these rings are composed of actin filaments and myosin motors (actomyosin) that, upon activation, trigger ring constriction. Actomyosin ring constriction, in turn, has been implicated in key cellular processes ranging from cytokinesis to wound closure. Non-constricting actin ring-like structures also form at cell-cell contacts, where they exert a stabilizing function. Here, we review recent studies on the formation and function of actin ring-like structures in various morphogenetic processes, shedding light on how those different rings have been adapted to fulfill their specific roles.


DOI

doi:10.1016/j.devcel.2016.05.024