preprint

Paper

/ bioRxiv

HAP40 functions as a proteostasis regulator by controlling huntingtin interactions and its release into the extracellular space

  • Eduardo Silva Ramos
  • Annett Boeddrich
  • Christian Haenig
  • Philipp Trepte
  • Orchid Ammar
  • Christopher Secker
  • Oliver Popp
  • Andranik Ivanov
  • Brandon Keith
  • Rachel J. Harding
  • Franziska Schindler
  • Tomas Koudelka
  • Leonard Roth
  • Nadine Scharek
  • Martina Zenkner
  • Nancy Neuendorf
  • Sabrina Golusik
  • Stephanie Beetz
  • Philipp Mertins
  • Ilaria Piazza
  • Sigrid Schnoegl
  • Erich E. Wanker
/ bioRxiv

HDAC inhibition via suberoylanilide hydroxamic acid (SAHA) ameliorates Doxorubicin-induced cardiotoxicity

  • Benay Eksi
  • Daniel Finke
  • Synje Michel
  • Jannek Brauer
  • Markus B. Heckmann
  • Mohsen Valadan
  • Leonard M. Schanze
  • Vighnesh Sunder
  • Hugo A. Katus
  • Norbert Frey
  • Johannes Backs
  • Lorenz H. Lehmann
/ bioRxiv

FYCO1 improves postischemic cardiac remodeling via enhanced autophagic flux and attenuation of proinflammatory signaling

  • Frauke Senger
  • Susanne S. Hille
  • Anca Kliesow Remes
  • Tapan K. Baral
  • Abel Martin-Garrido
  • Nesrin Schmiedel
  • Christian Kuhn
  • Oliver J. Müller
  • Ashraf Y. Rangrez
  • Johannes Backs
  • Arica Beisaw
  • Jörg Heineke
  • Norbert Frey
/ bioRxiv

Cardiomyocyte autophagy promotes a pro-regenerative immune response during cardiac regeneration

  • Florian Constanty
  • Bailin Wu
  • Srishti Shekhar
  • Alina Bektimirova
  • Vasiliki Bakali
  • Lucia Blasco Almodovar
  • Frauke Senger
  • Norbert Frey
  • Arica Beisaw
/ bioRxiv

Platelet C5aR1 aggravates myocardial infarction through platelet–neutrophil interactions and CXCL4-dependent NET release

  • Nicolas Schommer
  • Shanshan Zhang
  • Henry Nording
  • Manuela Sauter
  • Jacob von Esebeck
  • Paul Schilf
  • Christian D. Sadik
  • Nancy Schanze
  • Nadine Gauchel
  • Muataz Ali Hamad
  • Krystin Krauel
  • Niklas Burkhard
  • Lukas A. Heger
  • Harald F. Langer
  • Daniel Duerschmied
/ bioRxiv

Selective class IIa HDAC inhibition reverses diastolic dysfunction in cardiometabolic HFpEF

  • Jiale Huang
  • Friederike Schreiter
  • Junyu Fan
  • Zihao Chen
  • Harikrishnareddy Paluvai
  • Coenraad Withaar
  • Christian U. Oeing
  • Ali Reza Saadatmand
  • Eric Schoger
  • Shaza Haydar
  • Adel Elsherbiny
  • Marco Hagenmüller
  • Karine Lapouge
  • Nuno Guimarães-Camboa
  • Inês Falcão-Pires
  • Nazha Hamdani
  • Almut Schulze
  • Sepp Jansen
  • Michael A. Nolan
  • Ralf Gilsbach
  • Rudolf A. de Boer
  • Matthias Dewenter
  • Johannes Backs
/ Research Square

Host and lifestyle factors associated with the anterior nares’ microbiome diversity and composition: a cross-sectional analysis based on the German National Cohort (NAKO)

  • Sven Kleine Bardenhorst
  • Hansjörg Baurecht
  • Heiko Becher
  • Klaus Berger
  • Hermann Brenner
  • Kathrin Günther
  • Volker Harth
  • Bernd Holleczek
  • Rudolf Kaaks
  • André Karch
  • Thomas Keil
  • Yvonne Kemmling
  • Muhammad N.K. Khattak
  • Bianca Klee
  • Carolina Klett-Tammen
  • Lilian Krist
  • Berit Lange
  • Michael Leitzmann
  • Wolfgang Lieb
  • Karin B. Michels
  • Rafael Mikolajczyk
  • Matthias Nauck
  • Katharina Nimptsch
  • Nadia Obi
  • Annette Peters
  • Tobias Pischon
  • Tamara Schikowski
  • Börge Schmidt
  • Matthias B. Schulze
  • Julia Six-Merker
  • Kerstin Wirkner
  • Maike Wolters
  • Sabrina Woltemate
  • Marius Vital
  • Nicole Rübsamen
/ arXiv

Better than average: spatially-aware aggregation of segmentation uncertainty improves downstream performance

  • Vanessa Emanuela Guarino
  • Claudia Winklmayr
  • Jannik Franzen
  • Josef Lorenz Rumberger
  • Manuel Pfeuffer
  • Sonja Greven
  • Klaus Maier-Hein
  • Carsten T. Lüth
  • Christoph Karg
  • Dagmar Kainmueller
/ Research Square

Combinatorial tumor suppressor gene targeting immortalizes primary pancreatic ductal cells, resulting in temporal, deterministic structural patterns across the genome

  • Matthäus Felsenstein
  • Mengwen Hu
  • Dou Ma
  • Jenny Tamboli
  • Cao Zhong Jing Jin
  • Ruonan Wang
  • Luan Xiao Hui
  • Frank Dubois
  • Christopher Neumann
  • Anna Dolnik
  • Karl Herbert Hillebrandt
  • Luna Haderer
  • Madalina Giurgiu
  • Anton Henssen
  • Kirsten Kübler
  • Johann Pratschke
  • Thomas Malinka
  • Igor Sauer
  • Laura Wood
  • Nicholas Roberts
/ bioRxiv

Atomic structure and plasticity of the CTX-MthK complex investigated by cryo-EM, NMR, and MD simulations

  • Denis Qoraj
  • Swantje Mohr
  • Yessenbek K. Aldakul
  • Thiemo Sprink
  • Carl Öster
  • Taoran Xiao
  • Peter Schmieder
  • Sascha Lange
  • Tillmann Utesch
  • Daniel Roderer
  • Shanshuang Chen
  • Han Sun
  • Adam Lange