Computational Biology

Data Science, the extraction of relevant insights from data, has firmly positioned itself at the forefront of health and life science research. Machine Learning and Deep Learning are foreseen to become key disruptive technologies within Data Science in translational research and personalized medicine applications. The cross-cutting focus area Data Science and Artificial Intelligence comprises research groups spanning MDC’s different research areas:

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Science

HAICORE: More than just computing power

Providing computing resources for scientific research – that’s the mission of Helmholtz AI Compute Resources, a Helmholtz Association initiative. The Max Delbrück Center has now joined the Karlsruhe Institute of Technology and Forschungszentrum Jülich in hosting the program.
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Press Release No. 11 Berlin

Joint Berlin Data & AI Center planned

Data-driven research is crucial for tackling societal challenges. In a collaboration that is so far unique, Berlin's Universities of Excellence, the Max Delbrück Center, and the Helmholtz-Zentrum Berlin, together with the Zuse Institute Berlin, aim to establish a powerful Data and AI Center.
3D molecular reconstruction of a lung tumor
Press Release No. 7 Berlin

Towards understanding tumors in 3D

Researchers in Nikolaus Rajewsky’s lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor’s cellular neighborhoods in 3D and identify potential targets for personalized cancer therapy. They describe their findings in two separate papers in “Cell Systems.”
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Press Release No. 5 Berlin

Inflammatory messenger fuels Alzheimer’s

Researchers from Charité – Universitätsmedizin Berlin and the Max Delbrück Center have detailed the precise mechanism through which the inflammatory signaling molecule IL-12 contributes to Alzheimer’s disease. The study was published in the journal “Nature Aging.”
Jakob Metzger
Science

The juggler of numbers

Jakob Metzger has developed a new generation of brain organoids that are easier to mass-produce and uniform. The data they provide on rare neurological diseases can speed up the time it takes to find new therapies.
2D map of gene expression in the metastatic lymph node
Press Release No. 15 Berlin

3D maps of diseased tissues at subcellular precision

An open-source platform developed by researchers in Nikolaus Rajewsky’s lab at the Max Delbrück Center creates molecular maps from patient tissue samples with subcellular precision, enabling detailed study and potentially enhancing routine clinical pathology. The study was published in “Cell.”
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Institute & Campus

No research without IT girls

Life sciences research generates enourmous amounts of data; their analysis is thus no longer possible without machine learning or artificial intelligence. On Girls' Day, students from grades 6 to 12 found out what female mathematicians and computer scientists do at the Max Delbrück Center.
Prof. Jens Reich – Bundesverdienstorden
Institute & Campus

Don’t retreat to splendid isolation

He is a molecular biologist and physician, a GDR civil rights activist and bioethicist, a person with integrity and a sense of community. Until 2022, he was an ombudsman at the Max Delbrück Center. We celebrate the 85th birthday of Professor Jens Reich.
Markus Mittnenzweig
Science

Following cells on their path to development

It borders on the miraculous how an entire animal emerges from a single egg cell. In order to understand the underlying molecular mechanisms, Markus Mittnenzweig is establishing the Computational and Developmental Biology Lab at the Max Delbrück Center.
Group picture of the Girls'Day participants at Campus Buch
Institute & Campus

Discovering IT jobs in biomedicine at Girls’Day

22 young women and girls had the opportunity to experience the day-to-day life of an IT specialist at the Corporate IT or as a researcher at the Max Delbrück Center in Berlin-Buch and Mitte during the Girls’Day event. Boys’Day was also held at the same time.