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Liver

Article

stained tissue sections of a mouse liver after base editing
Press Release No. 23 September 17, 2025 Berlin

Gene editing to treat inherited kidney disease

Researchers led by Michael Kaminski report in “Molecular Therapy” that they have used base editing to repair mutations that cause ADPKD. The approach reduced liver cysts in mice.
Light sheet microscopy image of the hepato-pancreato-biliary organ system and gastrointestinal tract of a mouse embryo
Science September 29, 2021

The regenerative power of progenitors

Studies at the MDC and the BIH have revealed that the liver, gallbladder and pancreas arise from a common pool of progenitor cells and that the supply of cells from this pool is inexhaustible. These findings may contribute to the development of new regenerative therapies, the researchers write in the journal “Nature”.
Cover-Art_Spagnoli
Science February 17, 2017

Inducing an identity crisis in liver cells may help diabetics

It is now possible to reprogram cells from the liver into the precursor cells that give rise to the...
Press Release No. 3 February 13, 2017 Berlin

Inducing an identity crisis in liver cells may help diabetics

First successful reprogramming of liver cells to pancreas progenitor cells based on a single factor
Discovery for tomorrow's medicine

Max Delbrück Center for Molecular Medicine in the Helmholtz Association
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Phone: +49 30 9406-0

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Berlin Institute for Medical Systems Biology of the Max Delbrück Center
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Hannoversche Straße 28
10115 Berlin
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Phone: +49 30 9406-1300

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Helmholtz-Institut für translationale AngioCardioScience (HI-TAC) des Max Delbrück Center

Standort Medizinische Fakultät Mannheim & Medizinische Fakultät Heidelberg der Universität Heidelberg

Phone: +49 30 9406-0

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