15th Berlin Summer Meeting - Exploring Disease Landscapes
Exploring Disease Landscapes
Harnessing single-cell multi-omics, imaging and computational models
Dear friends and colleagues,
After two virtual Berlin Summer Meetings, we are excited to host the 15th Berlin Summer Meeting: “Exploring Disease Landscapes”, which will once again take place on-site in the BIMSB research building on 8-9 September 2022.
The meeting will showcase approaches towards understanding disease from different angles, including imaging, investigation of gene regulatory mechanisms, data science, and single cell technologies.
In addition to a selection of keynote speakers, all participants are invited to submit an abstract to be considered for a presentation. Early career scientists are particularly encouraged to apply.
To utilize the full potential of finally being able to get together in person again, the program will feature interactive formats as well as opportunities to network and socialize.
We hope to be able to welcome you to the 15th Berlin Summer Meeting this September!
The BSM2022 Scientific Committee
Peran Hayes
Anna Oliveras Martinez
Luiz Gustavo Teixeira Alves
Emanuel Wyler
Registration
Attendance of the Berlin Summer Meeting 2022 is free of charge, but registration until 1 September 2022 is required for on-site attendance.
Since space in the large conference room is limited, we’d ask you to be mindful of resources and cancel your on-site participation if you should no longer be able to attend (via e-mail bsm@mdc-berlin.de).
Call for abstracts
We invite all Berlin Summer Meeting 2022 participants to submit an abstract for consideration for a selected talk (approximately 20 min plus 10 min discussion). Early career researchers are particularly encouraged to apply.
Abstracts may be composed of a text with a maximum length of 2500 characters including spaces. The deadline for abstract submission is 21 August 2022.
Selected speakers will be notified by 28 August 2022.
Venue
MDC (BIMSB)
Hannoversche Straße 28
10115 Berlin
Germany
Time
Program
Thursday, September 8, 2022
10:00 am - 10:15 am Welcome address by Nikolaus Rajewsky
Session 1: Gene Regulation
10:15 am – 11:00 am Noam Stern Ginossar
Weizmann Institute of Science, Rehovot, Israel
mRNA translation – a tug of war during viral infection
11:00 am – 11:20 am Konrad Chudzik
Max Planck Institute for Molecular Genetics, Berlin, Germany
Multi-omic single-cell profiling reveals nuclear envelope release precedes gene activation during mouse embryogenesis
11:20 am – 11:40 am Melyssa Minto
Duke University, Computational Biology and Bioinformatics, Durham, NC, USA
Multiomic analysis reveal novel co-factors in Zic-mediated gene regulation in the cerebellum
11:40 am – 12 pm Euphy Wu
University of North Carolina at Chapel Hill, Department of Biostatistics, NC, USA
Detecting isoform-level allelic imbalance accounting for inferential uncertainty
12:00 pm -1:45 pm Lunch break
Session 2: Single Cell Biology
1:45 pm – 2:30 pm Simon Haas
Berlin Institute of Health/BIMSB, MDC
Unlocking the mysteries of blood generation by integrated multimodal single-cell analyses
2:30 pm – 2:50 pm Ahmed N. Hegazy
Charité-Universitätsmedizin Berlin, Department of Gastroenterology, Infectious Diseases and Rheumatology/ Berlin Institute of Health, Core Unit Bioinformatics (CUBI)
Multi-omics profiling of the circulating immune cell landscape in inflammatory bowel disease identifies circulating predictors for non-response to anti-integrin treatment
2:50 pm – 3:10 pm Eric Lindberg
MDC
Pathogenic variants damage cell composition and single-cell transcription in cardiomyopathies
3:10 pm – 3:30 pm Maja-Celine Cwikla
BIMSB, MDC/Charité – Universitätsmedizin Berlin
Intercellular extrachromosomal DNA copy number heterogeneity in neuroblastoma
3:45 pm – 5:00 pm Round tables with speakers and PIs (on site only)
5:00 pm – 8:00 pm BBQ on the rooftop terrace
Friday, September 9. 2022
Session 3: Understanding Disease
10:15 am – 11:00 am Susanne Wegmann
DZNE, Berlin, Germany
Condensates of Tau – a nexus between function and pathology
11:00 am – 11:20 am Henri Niskanen
Max Planck Institute for Molecular Genetics, Berlin, Germany
Disruption of nucleolar phase separation in human genetic disease
11:20 am – 11:40 am Anna Oliveras
BIMSB, MDC
Tau and ApoE coalescence drives lipid dysregulation in Alzheimer’s disease
11:40 am – 12:00 pm Janita Mintcheva
BIMSB, MDC
Cell state transitions and dynamics in zebrafish heart regeneration
12:00 am – 1:45 pm Lunch break
12:15 pm – 1:30 pm Breakout session (on site only)
Session 4: Organoids
1:45pm – 2:30 pm Markus Morkel
Charité – Universitätsmedizin Berlin
Oncogenes, signaling networks and cell states in colorectal cancer organoids
2:30 pm – 2:50 pm Kimberly Hartl
Charité – Universitätsmedizin Berlin/BIMSB, MDC
P53 knock-out cells are locked in a regenerative state in the context of colitis
2:50 pm – 3:10 pm Julian Heuberger
Charité – Universitätsmedizin Berlin, Department of Hepatology and Gastroenterology/BIMSB, MDC
IFN-gamma primes colonic epithelia for regeneration
3:10 pm – 3:30 pm Milad Rezvani
Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA/Charité Universitätsmedizin Berlin, Department of Pediatrics, Division of Gastroenterology, Nephrology and Metabolic Medicine/Berlin Institute of Health, Center for Regenerative Therapies
Trajectory Lineage Analyses of Human Hemato-Hepatogenesis Organoids from Human Pluripotent Stem Cells
3:30 pm Closing remarks
Organizers
The BSM2022 Scientific Committee
Peran Hayes
Anna Oliveras Martinez
Luiz Gustavo Teixeira Alves
Emanuel Wyler