Muscular dystrophy

The UNIPRENEURS Initiative has recognized the entrepreneurial spirit of 20 professors, among them ECRC researcher Simone Spuler. As a co-founder of the startup MyoPax, she is pioneering stem cell technology to develop regenerative therapies for previously incurable muscle diseases.

The stem cell therapy developed by MyoPax, a spin-off from the Max Delbrück Center and Charité, could soon be helping children with previously incurable muscle diseases thanks to an accelerated approval process. The necessary clinical trial will start in the fall.

Employees of the Max Delbrück Center and the Experimental and Clinical Research Center are mourning the loss of Gisela Krebs, who has passed away at the age of 91. Since 2015, her foundation has been supporting muscle desease research.

MyoPax develops regenerative therapies for previously incurable muscle diseases. An interview with co-founders Prof. Simone Spuler and Dr. Verena Schöwel-Wolf, now board member and CEO respectively

Muscle cells are very good at repairing damage. But if this fails, stem cells step in to regenerate the tissue. Carmen Birchmeier investigates the molecular signaling pathways that underlie these and other vital mechanisms.

Organoids have to be fed and cared for continuously so that they can mature. So far, it is mostly a manual process – not suitable for industrial drug screening. Now, the European Research Council (ERC) has awarded Mina Gouti a Proof of Concept Grant to tackle scalability and reproducibility.

MyoPax, a new spin-off of the Max Delbrück Center and Charité, receives a 1.3 million euros loan to jump-start its entrepreneurial activities. The start-up develops regenerative therapies for previously incurable muscle diseases using its innovative muscle stem cell technology.

Medical interventions in the human body can prolong our lives. But where do we draw the line? Questions like these were the subject of the Salon Sophie Charlotte "Still, Life is Life" of the Berlin-Brandenburg Academy of Sciences and Humanities. The MDC was part of it.

There’s likely to be a fundamental difference between how a medical practicioner and an artist view genetic editing with CRISPR. But both perspectives reveal possible ways to shape life in nature. Science meets art: the Max Delbrück Center at the Salon Sophie Charlotte 2022 in Berlin.

In muscular dystrophies, there can also be a deterioration in the heart's function. For a study on such cardiac involvement, the German Society for Muscular Dystrophies (Deutsche Gesellschaft für Muskelkranke e.V.) has awarded ECRC researchers Jeanette Schulz-Menger and Edyta Blaszczyk the Ulrich Brodeßer FSHD Prize 2022.