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Grosswendt Lab

From Cell States to Function

Profile

Cells communicate with their neighbors to shape gene expression and cellular decisions. Our team of wet lab and computational biologists aims to decode the language of cells by addressing four central questions: (1) Which cells are neighbors? (2) How do they communicate? (3) What are the consequences? (4) Can we build cell interactions?

We develop single-cell- and spatial transcriptomics-based genomic strategies to investigate how cells interact, focusing on the communication patterns that instruct neural crest cells in the mouse embryo. Furthermore, we develop strategies in complex in vitro systems and reconstruct interactions bottom-up. Ultimately, we aim to understand how cell interactions are organized and collectively instruct cells.

The group is part of the joint Single Cell Approaches for Personalized Medicine’ Research Focus Area of the Berlin Institute of Health (BIH) at Charité and the Max-Delbrück Center for Molecular Medicine (MDC). Our lab is located at the Berlin Institute of Medical Systems Biology of the MDC, and we closely collaborate with the clinical Department of Pediatric Oncology and Hematology at the Charité.

Team

Group Leader 

Stefanie Grosswendt

101: Berlin Institute for Medical System Biology
Room: 5.42
stefanie.​grosswendt@​mdc-​berlin.​de
+49 30 94061427 – 1427

Postdocs

Elmir Mahammadov
101: Berlin Institute of Medical Systems Biology
Room: 5.4449
elmir.​mahammadov@​mdc-​berlin.​de
+49 30 9406 – 1417

PhD students

Tobias Christaller

101: Berlin Institute of Medical Systems Biology
Room: 5.4449
Tobias.​Christaller@​mdc-​berlin.​de
+49 30 9406 – 1417

Michael Eibl

101: Berlin Institute of Medical Systems Biology
Room: 5.4449
+49 30 9406 – 1417


Melanie Fattohi

101: Berlin Institute of Medical Systems Biology
Room: 5.4449
melanie.​fattohi@​mdc-​berlin.​de
+49 30 9406 – 1417
Fabian Gademann
 
101: Berlin Institute of Medical Systems Biology
Room: 5.4449
+49 30 9406 – 1417
Matthew Hare
101: Berlin Institute of Medical Systems Biology
Room: 5.4449
matthew.​hare@​mdc-​berlin.​de
+49 30 9406 – 1417
Shriya Lele
101: Berlin Institute of Medical Systems Biology
Room: 5.4449
shriya.​lele@​mdc-​berlin.​de
+49 30 9406 – 1417

Henrike Scherrer
101: Berlin Institute of Medical Systems Biology
Room: 5.4449
henrike.​scherrer@​mdc-​berlin.​de
+49 30 9406 – 1417


Philipp Stachel-Braum

MDC-NYU Fellowship
101: Berlin Institute of Medical Systems Biology
Room: 5.4449
Philipp.​Stachel-​Braum@​mdc-​berlin.​de
+49 30 9406 – 1417

Lab Manager

Maria Will

101: Berlin Institute of Medical Systems Biology
Room: 5.4449
Maria.​Will@​mdc-​berlin.​de
+49 30 9406 – 1595

Team Assistance

Juliane Großkopf

101: Berlin Institute of Medical Systems Biology
Room: 4.01
Juliane.​Grosskopf@​mdc-​berlin.​de
+49 30 9406 – 1452

Alumni

Leon Elias Kersting
Master student
Bárbara Zita Peters Couto
Master student

Publications

News

Jobs

Hiring:

Candidates interested in postdoc or PhD positions please contact Stefanie Grosswendt. Please provide your CV including names of at least two referees, a letter of motivation, and when applying for a PhD position, please also include your transcript of records listing the courses and grades of your university degree. We especially encourage applications by computational scientists for PhD and Postdoc positions. Computational PhD candidates can participate in the CompCancer program that our group is associated with.