MDC-BIMSB

Since 2008, the Berlin Institute for Medical Systems Biology (MDC-BIMSB) has expanded the research profile of the Max Delbrück Center. The researchers at MDC-BIMSB want to understand how genes regulate the lives of cells in health and disease. This requires the Institute’s research groups to break down the traditional boundaries between disciplines such as biotechnology, computational science, biochemistry, molecular biology, and clinical research.

Further informationen on MDC-BIMSB

Article

People in the lab
Press Release No. 12 Berlin

Virtual reality, video mapping, and a walk-through vein

A VR journey into microplastics in the brain, a walk-through vein, a laboratory transformed into an escape room: The Max Delbrück Center is hosting 65 events as part of the Long Night of the Sciences. Visitors will get a look at how our researchers’ work is shaping the medicine of tomorrow.
Microscopic image of a bone marrow biopsy
Press Release No. 11 Berlin

How blood stem cells diversify

Different types of bone marrow stem cells give rise to blood and immune cells. A team led by Simon Haas now reports in “Nature Cell Biology” how that diversity develops. The findings could help improve stem cell therapies, including treatments for blood cancers.
A day-old micropatterned organoid generated from induced pluripotent stem cells (iPSCs) derived from a patient with a mutation in the IRF2BPL gene. The different colors mark distinct cell populations, which reveal how the organoid is organizing into layers of developing neural tissue. It provides a snapshot of early human brain-like development in this patient-derived model.
Institute & Campus By Gunjan Sinha

NEDAMSS patients and scientists meet

Families, researchers, and clinicians will gather in Berlin to share knowledge and build momentum toward therapies for NEDAMSS, a rare neurodevelopmental disorder. Jakob Metzger, Group Leader of the Quantitative Stem Cell Biology lab explains why this day matters and what participants can expect.
Scientific image
Science

Fat tissue fuels gut inflammation

Researchers at the Max Delbrück Center and Charité – Universitätsmedizin Berlin show that adipose tissue amplifies gut inflammation in Crohn’s disease. The study, published in the “Journal of Clinical Investigation,” also reveals how genetic changes in immune cells may contribute to the disease.
Ludwig Leif
Science

Leif Si-Hun Ludwig awarded professorship

Leif Si-Hun Ludwig has been awarded a prestigious Heisenberg professorship in stem cell dynamics and mitochondrial genomics by the the Berlin Institute of Health at Charité, a position funded by the German Research Foundation (DFG).
Nikolaus Rajewsky und Leif Sander
Science

A new opportunity for Berlin

The Einstein Center for Early Disease Interception has been funded with six million euros. In an interview, Nikolaus Rajewsky and Leif Erik Sander, both spokespeople of the center, explain why new technologies and cross-institutional collaboration will make disease prevention in the future possible.
Friedemann Paul und Nikolaus Rajewsky
Science

Influential in their fields

According to a ranking by Clarivate, Friedemann Paul and Nikolaus Rajewsky are among the most Highly Cited Researchers in the world. Both made the list repeatedly. Germany ranks fourth of countries and regions, behind the U.S., mainland China and the U.K.
Discoverers
Press Release No. 27 Berlin

Sharks, microbes and a world première

Berlin Science Week 2025 kicks off on November 1. The Max Delbrück Center invites science enthusiasts to talks and tours, a concert, and exhibitions highlighting our research and to join discussions on a wide range of topics.
Mosquito
Press Release No. 24 Berlin

How malaria harms unborn babies

U.K.-based Wellcome has awarded over €2 million to an international research effort to uncover how malaria can injure developing babies. Emanuel Wyler at the Max Delbrück Center will play a key role in studying the molecular interaction between the parasite Plasmodium falciparum and the placenta.
five people
Science

Five Berlin-based leading minds honored

Five scientists from the Max Delbrück Center have been named among the 100 most important minds in Berlin science in 2025 by the newspaper Tagesspiegel: Simone Spuler, Clara Vázquez García, Thoralf Niendorf, Gabriele Schiattarella and Ana Pombo.