Systematic perturbation of chromatin factors identifies regulatory networks during healthy and malignant hematopoiesis

Autor/innen

  • L. Solé-Boldo
  • S. Haas

Journal

  • Nature Genetics

Quellenangabe

  • Nat Genet 55 (9): 1430-1431

Zusammenfassung

  • In this issue of Nature Genetics, Lara-Astiaso et al. systematically characterized the functional roles of several chromatin factors in hematopoiesis by combining functional CRISPR screens with single-cell transcriptomics and chromatin accessibility profiling, revealing lineage biases and relationships with important transcription factors.


DOI

doi:10.1038/s41588-023-01478-9