Wissenschaftliche Publikationen

Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3

K.Y. Chen
T. Kibayashi
A. Giguelay
M. Hata
S. Nakajima
N. Mikami
Y. Takeshima
K. Ichiyama
R. Omiya
L.S. Ludwig
K. Hattori
S. Sakaguchi

Clonal tracing with somatic epimutations reveals dynamics of blood ageing

M. Scherer
I. Singh
M.M. Braun
C. Szu-Tu
P. Sanchez Sanchez
D. Lindenhofer
N.A. Jakobsen
V. Körber
M. Kardorff
L. Nitsch
P. Kautz
J. Rühle
A. Bianchi
L. Cozzuto
R. Frömel
S. Beneyto-Calabuig
C. Lareau
A.T. Satpathy
R. Beekman
L.M. Steinmetz
S. Raffel
L.S. Ludwig
P. Vyas
A. Rodriguez-Fraticelli
L. Velten

03. April 2025 / bioRxiv

Coordinated IFN-γ/TNF axis drives selective loss of activated enteric glia in inflammatory bowel diseases

M. Bubeck
K.A. Penkert
H. Limberger
M. González Acera
C. Plattner
S. Ziegler
A.N. Muppirala
P. Forster
M. Jakob
R. Gamez-Belmonte
L. Erkert
S. Kulkarni
C. Günther
R. Atreya
A.A. Kühl
A. Hegazy
K. Hildner
Z. Trajanoski
B. Siegmund
M.F. Neurath
M. Rao
F. Progatzky
D.C. Lie
C. Becker
C. Romagnani
L.S. Ludwig
C.S.N. Klose
J.V. Patankar

The chromatin accessibility landscape of pediatric AML

A.M. Giguelay
L.S. Ludwig

The next generation of in situ multi-omics

M. Salla
K. Penkert
L.S. Ludwig

Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencing

T. Abay
R.R. Stickels
M.T. Takizawa
B.N. Nalbant
Y.H. Hsieh
S. Hwang
C. Snopkowski
K.K.H. Yu
Z. Abou-Mrad
V. Tabar
B.E Howitt
L.S. Ludwig
R. Chaligné
A.T Satpathy
C.A. Lareau

Tissue-specific apparent mtDNA heteroplasmy and its relationship with ageing and mtDNA gene expression

S. Wengert
X. Giannoulis
P. Kreitmaier
P. Kautz
L.S. Ludwig
H. Prokisch
F.P. Casale
M. Heinig
N. Cai

Tracking rare single donor and recipient immune and leukemia cells after allogeneic hematopoietic cell transplantation using mitochondrial DNA mutations

L. Penter
N. Cieri
K. Maurer
M. Kwok
H. Lyu
W.S. Lu
G. Oliveira
S.H. Gohil
I. Leshchiner
C.A. Lareau
L.S. Ludwig
D.S. Neuberg
H.T. Kim
S. Li
L. Bullinger
J. Ritz
G. Getz
J.S. Garcia
R.J. Soiffer
K.J. Livak
C.J. Wu

Artifacts in single-cell mitochondrial DNA mutation analyses misinform phylogenetic inference

C.A. Lareau
M.S. Chapman
L. Penter
T. Nawy
D. Pe’er
L.S. Ludwig

Mitochondrial genetics through the lens of single-cell multi-omics

L. Nitsch
C.A. Lareau
L.S. Ludwig