Daumke Lab
Structural Biology of Membrane-Associated Processes
Profile
GTPases of the dynamin and septin superfamilies are molecular machines that assemble at the surface of cellular membranes.
Some of these proteins act as dynamic scaffolds that remodel the underlying membrane in a GTPase-dependent fashion; others orchestrate the recruitment of interaction partner in a temporally and spatially defined manner.
We are interested to understand principles of assembly, function and regulation of these GTPases. To this end, structural studies are combined with biochemical and cell-based approaches.
Team
Research
Projects
A short overview on our projects on dynamin superfamily proteins (dynamin, DNM1L, MxA), GIMAPs, and stomatin proteins is shown in the corresponding sections.
