ECRC

As a common structure established by the Max Delbrück Center for Molecular Medicine (MDC) and the Charité Medical Faculty in Berlin, the ECRC integrates a critical mass of committed clinician/scientists and translational researchers in the research-driven environment on the MDC Campus in Berlin-Buch and offers excellent opportunities for education in translational research and the development of clinician scientist careers.

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Group picture of the Girls'Day participants at Campus Buch
Institute & Campus

Discovering IT jobs in biomedicine at Girls’Day

22 young women and girls had the opportunity to experience the day-to-day life of an IT specialist at the Corporate IT or as a researcher at the Max Delbrück Center in Berlin-Buch and Mitte during the Girls’Day event. Boys’Day was also held at the same time.
Scientific image
Press Release No. 16 Berlin

How cancer genes become independent

Sometimes a tumor suddenly starts growing rapidly or becomes resistant to cancerdrugs. This can be caused by a cancer gene “striking out on its own” in ring shapes. ECRC-scientist Anton Henssen described how these DNA rings arise and continue to develop in the journal “Nature Genetics”.
Mensch im Labor
Science

Improving cancer diagnosis with quantum technology

Partners in industry and research are aiming to optimise the diagnosis of cancer and other diseases with a novel microscopy technique. The QEED research project has been allocated a two-figure million sum in funding. ECRC scientist Hendrik Bartolomaeus is a member of the consortium.
Scientific image
Press Release No. 11 Berlin

Novel disease models for multiple myeloma

A team of scientists led by Martin Janz and Klaus Rajewsky at the Max Delbrück Center has successfully generated genetically defined mouse models for two subtypes of multiple myeloma. These models will contribute to a better understanding of how the disease develops in humans. The team has now published their findings in the journal PNAS.
Dominik Müller
Science

The salt scientist

Dominik Müller investigates how lifestyle affects the molecular regulation processes in the body – such as how a high-sodium diet impacts the immune system and cardiovascular health. In doing so, he deliberately transcends the boundaries between disciplines.
Simone Spuler und Verena Schöwel-Wolf
Institute & Campus

Deep expertise, and a bold vision: MyoPax launches in Berlin

MyoPax develops regenerative therapies for previously incurable muscle diseases. An interview with co-founders Prof. Simone Spuler and Dr. Verena Schöwel-Wolf, now board member and CEO respectively
Salt on table
Press Release No. 6 Berlin

Salt cuts off the energy supply to immune regulators

Regulatory T cells ensure that immune responses happen in a controlled way. But eating too much salt weakens these cells’ energy supply, thus rendering them dysfunctional for a while. This may have implications for autoimmunity, an international team – including Dominik Müller – reports in “Cell Metabolism.”
Microscopic image of IRF4
Press Release No. 1 Berlin

Inborn immunodeficiency discovered – and explained

A group of international researchers – among them Stephan Mathas from the ECRC – has found that changing a single segment of the genome causes a previously unknown immunodeficiency in humans. The paper, which appears in Science Immunology, reports the discovery of a point mutation in the transcription factor IRF4.
Il-Kang Na
Science

Il-Kang Na heads Clinician Scientist Program

Il-Kang Na, BIH Johanna Quandt Professor and head of a research group at the Experimental and Clinical Research Center (ECRC), became the new director of the BIH Charité Clinician Scientist Program on January 1, 2023. Her own journey has made her a role model for aspiring clinician scientists.
Biobank
Science

Understanding the transition to disease

As part of the IMMEDIATE project, a team led by ECRC researcher Friedemann Paul is investigating inflammatory precursors of diseases – and how nutrition and the gut microbiome influence the immune system. The project is receiving more than €7 million in EU funding.