Max Delbrück Center MDC - Max-Delbrück-Centrum für molekulare Medizin in der Helmholtz-Gemeinschaft

Our Research

Research at the Max Delbrück Center aims to elucidate the molecular mechanisms of health and disease, and translate those findings into medical practice.

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Data Science and Artificial Intelligence

Enabling multi-modal prediction from molecules to cohorts.

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Research Highlights

Our research teams publish around 450 specialist articles every year. Our research highlights can be found here, presented in a comprehensible format.

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Selection of research highlights
induced pluripotent stem cells in a pluripotency test

Research News & Events

Messenger RNA strand 3D rendering
Science

How cellular quality control works

Markus Landthaler and colleagues from the University of Cologne have deciphered the rules of a key cellular quality control mechanism in detail, and published their results in “Molecular Cell.”
This digital illustration depicts a cancer cell in the blood stream.

Using deep learning for precision cancer therapy

Altuna Akalin and his team present a tool in “Nature Communications” that applies deep neural networks to evaluate multimodal data to help doctors choose the best treatment for their cancer patients.
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Uncovering hidden gene switches

The Ohler lab has developed a new method called TESLA-seq to identify regulatory regions in the human genome. The research was published in “Cell Genomics.”
Dominik Müller
Science

Dominik Müller is honored in the US

The American Heart Association has awarded its Excellence Award for Hypertension Research to Dominik Müller from the Max Delbrück Center. He is only the third European to be honored with this distinction from the oldest professional society in the U.S.
Mahak Singhal
Science

HI-TAC researcher Mahak Singhal receives ERC grant

The European Research Council awards an ERC Starting Grant to HI-TAC guest researcher Mahak Singhal. He will investigate how the lining of our blood vessels senses, anticipates, and responds to the circadian changes between day and night.
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Markus Mittnenzweig wins ERC Starting Grant

Markus Mittnenzweig of the Max Delbrück Center has been awarded a €1.5 million grant from the European Research Council. He and his team will build dynamic 3D models of how neighboring cells and gene activity guide early-stage embryonic zebrafish cells to become specialized tissues.
Ashley Sanders
Science

Professorship awarded to Ashley Sanders

Ashley Sanders has been awarded a full professorship from Charité –Universitätsmedizin Berlin. The tenured position will enable her and her team to expand their research on developing personalized therapies for inflammatory bowel disease and other conditions.
Biopolis Podcast Header
Science

“These organisms help define who we are”

Can microbiome science be engaging, entertaining, and educational? Absolutely, as shown by “Biopolis.” In the podcast, Chemist Theda Bartolomaeus and producer Michiel van Poelgeest take listeners on a journey into a hidden universe.
Igor Maciel Souza Silva
Science

Igor Maciel Souza Silva wins Marie Curie Fellowship

Igor Maciel Souza Silva has been awarded a 2-year Marie Curie fellowship. With his grant, he will investigate the structure of the epidermal growth factor receptor, which contributes to the development of cancer. He hopes the research will lead to safer cancer therapies.

All News & Events

Publications

Rbm8a deficiency causes hematopoietic defects by modulating Wnt/PCP signaling

Dev Biol

Editorial overview: mathematical modeling of disease processes

Curr Opin Syst Biol

How vascularization is reciprocally coupled to chondrogenesis and osteogenesis in bone healing: lessons from the growth plate

Bone

Advanced peptide nanoparticles enable robust and efficient delivery of gene editors across cell types

J Control Release

All Publications