Farewell Symposium for Thomas Sommer
Targeted proteolysis: From basic discovery to clinical application
Join us for a special scientific symposium as we celebrate the remarkable career of Professor Thomas Sommer. For more than three decades, Thomas Sommer has pioneered research on ubiquitin and targeted proteolysis at the Max Delbrück Center, providing key insights into how misfolded proteins are identified and degraded within cells. In addition to his outstanding scientific achievements, he has also served as a director at the Max Delbrück Center, shaping the institute’s scientific direction and ambition. As he embarks on the next chapter of his career, we honor his legacy and the profound impact of his work on targeted proteolysis and beyond.
The event will bring together leading researchers from around the world to share insights into the latest advances in ubiquitin biology and targeted proteolysis. Special emphasis will be placed on recent developments in the rapidly evolving field of targeted protein degradation (TPD), which has progressed from proof of concept to the development of degrader drugs currently in clinical trials. The symposium will prioritize in-person exchanges to maximize interactions, stimulate questions, and foster new collaborations.
- Confimed Speakers
Aaron Ciechanover
Technion - Israel Institute of Technology, Haifa
Ivan Đikić
Goethe University, Frankfurt
Fleur M. Ferguson
University of California, San DiegoRuth Geiss-Friedlander
Albert Ludwig University, FreiburgSonja Lorenz
MPI for Multidisciplinary Sciences, GöttingenRadosław Nowak
University of BonnMichael Potente
Berlin Institute of Health at CharitéBrenda Schulman
MPI of Biochemistry, Martinsried- Preliminary Program
TARGETED PROTEOLYSIS: FROM BASIC DISCOVERY TO CLINICAL APPLICATION
08:30 Registration and welcome coffee 09:00 Opening and Welcome
Maike Sander, Scientific Director, Max Delbrück Center, Berlin
Chair: tba 09:15 Keynote lecture
The Embarrassingly Simple Discovery of the Ubiquitin System
Aaron Ciechanover, Technion - Israel Institute of Technology, Haifa10:00 E3 Ligase Mechanisms: From Endogenous Regulation to Targeted Protein Degradation
Brenda Schulman, MPI of Biochemistry, Martinsried10:30 Coffee break Chair: Evangelia Nathanail, Max Delbrück Center, Berlin 11:00 Specificity Mechanisms of HECT-Type Ubiquitin Ligases
Sonja Lorenz, MPI for Multidisciplinary Sciences, Göttingen11:30 Tba
Ruth Geiss-Friedlander, Albert Ludwig University, Freiburg12:00 Lunch break Chair: Joseph Lim, Max Delbrück Center, Berlin 13:15 Targeting Ubiquitin and Autophagy Networks in Cancer
Ivan Đikić, Goethe University, Frankfurt13:45 Keynote lecture
Interrogating the Druggable Proteome with Proximity Pharmacology
Fleur M. Ferguson, University of California, San Diego14:30 Coffee break Chair: Jorge Andrade, Max Delbrück Center, Berlin 15:00 Targeting C2H2 Transcription Factors for Degradation with Molecular Glues
Radosław Nowak, University of Bonn15:30 Deconvolution of Complex Biological (vascular) Processes Through Targeted Protein Degradation
Michael Potente, Max Delbrück Center16:00 Official farewell
conclusions Thomas Sommer, Maike Sander17:00 Reception 18:00 After hour - How to get to the venue
Venue
Max Delbrück Center
Robert-Rössle-Straße 10
13125 Berlin
Deutschland
Zeit
Organisator*innen
Oliver Daumke
If you have any questions, please contact events@mdc-berlin.de.