Circulating concentrations of folate and vitamin B12 in relation to prostate cancer risk: results from the European Prospective Investigation into Cancer and Nutrition study
Autor/innen
- M. Johansson
- P.N. Appleby
- N.E. Allen
- R.C. Travis
- A.W. Roddam
- L. Egevad
- M. Jenab
- S. Rinaldi
- L.A. Kiemeney
- H.B. Bueno-de-Mesquita
- S.E. Vollset
- P.M. Ueland
- M.J. Sanchez
- J.R. Quiros
- C.A. Gonzalez
- N. Larranaga
- M.D. Chirlaque
- E. Ardanaz
- S. Sieri
- D. Palli
- P. Vineis
- R. Tumino
- J. Linseisen
- R. Kaaks
- H. Boeing
- T. Pischon
- T. Psaltopoulou
- A. Trichopoulou
- D. Trichopoulos
- K.T. Khaw
- S. Bingham
- G. Hallmans
- E. Riboli
- P. Stattin
- T.J. Key
Journal
- Cancer Epidemiology Biomarkers & Prevention
Quellenangabe
- Cancer Epidemiol Biomarkers Prev 17 (2): 279-285
Zusammenfassung
Determinants of one-carbon metabolism, such as folate and vitamin B(12), have been implicated in cancer development. Previous studies have not provided conclusive evidence for the importance of circulating concentrations of folate and vitamin B(12) in prostate cancer etiology. The aim of the present study was to investigate the relationship between prostate cancer risk and circulating concentrations of folate and vitamin B(12) in a large prospective cohort.