Project Funding for “Single cell approaches in personalized medicine”
BIH/Charité/MDC focus area
A summary of each project will be published soon.
Project overview
Funding call in 2024
Katrin de la Rosa | Il-Kang Na | Dieter Beule: lnfluence of intrinsic and extrinsic factors on 8‑cell reconstitution and adaptation following allogeneic hematopoietic stem cell transplantation
Janine Altmüller | Ulrich Keller | Francis Baumgartner | Nils Blüthgen: Resolving the cellular ecosystem of high-risk uveal melanoma for novel therapeutic interventions
Markus Landthaler | Markus Morkel: Studying therapeutic drug responses in colorectal cancer ex vivo organotypic cultures using spatial SLAM-seq
Agnieszka Rybak-Wolf | Sarah Shoichet: Deciphering the Temporal and Cell-Type Specific Expression of Disease-Associated SynGAP Gene Isoforms During Human Brain Development
Manuel Irimia | Nikolaus Rajewsky | Steffen Fuchs: Spatial dissection of alternative splicing linked to resistance in neuroblastoma
Michael Robson | Simone Spuler: Optimising cell-based muscular dystrophy therapies with single-cell multi-omics
Funding call in 2025
Friedemann Paul | Stefan Gold: X — chromosomal mechanisms as sex — specific drivers of Neuromyelitis optica spectrum disorders
Janine Altmüller | Francis Baumgartner | Stefanos Bampopoulos: Resolving Tebentafusp-driven changes in the Cellular Ecosystem of Uveal Melanoma for Targeted Treatment Strategies Collaborating
Michael Kaminski | Michael Balzer | Jan Halbritter: Single-cell Personalized Medicine for ADPKD: Revealing Key Pathways Leveraging a Founder Mutation (SPARK- FM)
Fabian Coscia | Ingeborg Keilholz: Proteomic Profiling of Single Circulating Tumor Cells
Volker Siffrin | Leif Erik Sander | Nina Babel: HUSTLEseq: High-throughput unbiased TCR-epitope linking scRNAseq: Uncovering JCV-specific T‑cells in PML patients
Leif Ludwig | Thomas Conrad | Livius Penter: RNA Flex-based integrated transcriptome profiling with single nucleotide variant genotyping
Rogier Versteeg | Marvin Jens | Nikolaus Rajewsky: Single cell and spatial transcriptomics analysis of neuroblastoma relapse models to define gene modules for therapeutic targeting