AG Birol

Profil

Team

Leiter

Dr. Melissa Birol

101: Berlin Institute for Medical System Biology

Raum: 2.41

Melissa.Birol@mdc-berlin.de

Sekretariat

Feraye Kocaoglu

Feraye.Kocaoglu@mdc-berlin.de

+49 30 9406-1425

Doktorand

Isabella Ioana Douzoglou Munoz

Isabella.Douzoglou@mdc-berlin.de

Johanna Elisabeth Fritsch

JohannaElisabeth.Fritsch@mdc-berlin.de

Melina Patsonis

Melina.Patsonis@mdc-berlin.de

Paula Santos Otte

Paula.SantosOtte@mdc-berlin.de

Student

Maximilian Freilinger

Maximilian.Freilinger@mdc-berlin.de

Forschung

Veröffentlichungen

10. Januar 2020 in Front Mol Neurosci

Untangling the conformational polymorphism of disordered proteins associated with neurodegeneration at the single-molecule level

• M. Birol
• A.M. Melo

18. Juni 2019 in PLoS Biol

Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein

• M. Birol
• S.P. Wojcik
• A.D. Miranker
• E. Rhoades

03. April 2018 in Nat Commun

Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid

• M. Birol
• S. Kumar
• E. Rhoades
• A.D. Miranker

01. April 2018 in Curr Opin Struct Biol

IDPs in macromolecular complexes: the roles of multivalent interactions in diverse assemblies

• H.Y.J. Fung
• M. Birol
• E. Rhoades

01. Januar 2018 in Methods Enzymol

Targeting the intrinsically disordered proteome using small-molecule ligands

• S. Wójcik
• M. Birol
• E. Rhoades
• A.D. Miranker
• Z.A. Levine

11. Mai 2016 in Chem Commun

Foldamer scaffolds suggest distinct structures are associated with alternative gains-of-function in a preamyloid toxin

• S. Kumar
• M. Birol
• A.D. Miranker

25. April 2016 in Nat Commun

Foldamer-mediated manipulation of a pre-amyloid toxin

• S. Kumar
• M. Birol
• D.E. Schlamadinger
• S.P. Wojcik
• E. Rhoades
• A.D. Miranker

21. August 2014 in PLoS One

Structural and biochemical characterization of the Cop9 signalosome CSN5/CSN6 heterodimer

• M. Birol
• R.I. Enchev
• A. Padilla
• F. Stengel
• R. Aebersold
• S. Betzi
• Y. Yang
• F. Hoh
• M. Peter
• C. Dumas
• A. Echalier

01. Januar 2014 in Curr Protein Pept Sci

Structure and function of MPN (Mpr1/Pad1 N-terminal) domain-containing proteins

• M. Birol
• A. Echalier

22. Januar 2013 in Proc Natl Acad Sci U S A

Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1

• A. Echalier
• Y. Pan
• M. Birol
• N. Tavernier
• L. Pintard
• F. Hoh
• C. Ebel
• N. Galophe
• F.X. Claret
• C. Dumas

Nachrichten

Wissenschaft 12. Januar 2021

Was tanzende Spaghetti im Gehirn anrichten

Von Haus aus theoretische Biohysikerin, erforscht Melissa Birol ab Dezember 2020 als neue Juniorgruppenleiterin am MDC Verhalten und Funktion ungeordneter Proteine in den Hirnzellen.