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© Jakob Metzger, MDC

AG Metzger

Quantitative Stem Cell Biology

Informationen zu unserer Arbeitsgruppe finden Sie auf der englischen Seite.

Team

Leiter

Dr. Jakob Johannes Metzger
Dr. Jakob Johannes Metzger
101: Berlin Institute for Medical System Biology
Raum: 2.42
+49 30 9406-1340

Wissenschaftler

Dr. Pawel Lisowski
101: Berlin Institute for Medical System Biology
Raum: 2.44-49
+49 30 9406-1340

Sekretariat

Feraye Kocaoglu
Feraye Kocaoglu
+49 30 9406-1425

Technischer Assistent

Mandy Gerlach
101: Berlin Institute for Medical System Biology
Raum: 2.82-89
+49 30 9406-1370
Stephanie Petzold
101: Berlin Institute for Medical System Biology
Raum: 2.82-89
+49 30 9406-1370

Mitarbeiter

Anja Vanessa Kirsch
101: Berlin Institute for Medical System Biology
Raum: 2.72-76

Doktorand

Cassandra Carao Caedo
Cassandra Carao Caedo
101: Berlin Institute for Medical System Biology
Raum: 2.82-89
Francesca Dal Pozzolo
Francesca Dal Pozzolo
101: Berlin Institute for Medical System Biology
Raum: 2.82-89
+49 30 9406-1370

Veröffentlichungen

/ EMBO Mol Med

CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment

  • R. Greensmith
  • I.T. Lape
  • C.V. Riella
  • A.J. Schubert
  • J.J. Metzger
  • A.S. Dighe
  • X. Tan
  • B. Hemmer
  • J. Rau
  • S. Wendlinger
  • N. Diederich
  • A. Schütz
  • L.V. Riella
  • M.M. Kaminski
/ Nat Commun

Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure

  • P. Lisowski
  • S. Lickfett
  • A. Rybak-Wolf
  • C. Menacho
  • S. Le
  • T.M. Pentimalli
  • S. Notopoulou
  • W. Dykstra
  • D. Oehler
  • S. López-Calcerrada
  • B. Mlody
  • M. Otto
  • H. Wu
  • Y. Richter
  • P. Roth
  • R. Anand
  • L.A.M. Kulka
  • D. Meierhofer
  • P. Glazar
  • I. Legnini
  • N.S. Telugu
  • T. Hahn
  • N. Neuendorf
  • D.C. Miller
  • A. Böddrich
  • A. Polzin
  • E. Mayatepek
  • S. Diecke
  • H. Olzscha
  • J. Kirstein
  • C. Ugalde
  • S. Petrakis
  • S. Cambridge
  • N. Rajewsky
  • R. Kühn
  • E.E. Wanker
  • J. Priller
  • J.J. Metzger
  • A. Prigione
/ Front Neurosci

Novel human neurodevelopmental and neurodegenerative disease associated with IRF2BPL gene variants-mechanisms and therapeutic avenues

  • D. Bauersachs
  • L. Bomholtz
  • S. Del Ray Mateos
  • R. Kühn
  • P. Lisowski
/ Stem Cell Res

Generation of an induced pluripotent stem cell line from a Huntington's disease patient with a long HTT-PolyQ sequence

  • D.C. Miller
  • P. Lisowski
  • C. Genehr
  • E.E. Wanker
  • J. Priller
  • A. Prigione
  • S. Diecke
/ Adv Med Sci

Genome-engineering technologies for modeling and treatment of cystic fibrosis

  • M. Dębczyński
  • D. Mojsak
  • Ł. Minarowski
  • M. Maciejewska
  • P. Lisowski
  • R.M. Mróz
/ Cell Rep

Mechanisms of IRF2BPL-related disorders and identification of a potential therapeutic strategy

  • S. Sinha Ray
  • D. Dutta
  • C. Dennys
  • S. Powers
  • F. Roussel
  • P. Lisowski
  • P. Glažar
  • X. Zhang
  • P. Biswas
  • J.R. Caporale
  • N. Rajewsky
  • M. Bickle
  • N. Wein
  • H.J. Bellen
  • S. Likhite
  • P.C. Marcogliese
  • K.C. Meyer
/ Stem Cell Res

Generation of induced pluripotent stem cells from three individuals with Huntington's disease

  • D.C. Miller
  • P. Lisowski
  • S. Lickfett
  • B. Mlody
  • M. Bünning
  • C. Genehr
  • C. Ulrich
  • E.E. Wanker
  • S. Diecke
  • J. Priller
  • A. Prigione
/ Cell Rep Methods

Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington's disease models

  • J.J. Metzger
  • C. Pereda
  • A. Adhikari
  • T. Haremaki
  • S. Galgoczi
  • E.D. Siggia
  • A.H. Brivanlou
  • F. Etoc
/ Reprod Biol

Deletion in the Y chromosome of B10.BR-Y(del) mice alters transcription from MSYq genes and has moderate effect on DNA methylation

  • K. Kotarska
  • A. Doniec
  • M. Korostyński
  • M. Piechota
  • A. Gołas
  • P. Lisowski
  • J. Styrna
/ Development

Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects

  • S. Galgoczi
  • A. Ruzo
  • C. Markopoulos
  • A. Yoney
  • T. Phan-Everson
  • S. Li
  • T. Haremaki
  • J.J. Metzger
  • F. Etoc
  • A.H. Brivanlou

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